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Nimustine (hydrochloride) [55661-38-6]

HY-13703A
MedChem Express
Product group Molecular Biology
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Nimustine (hydrochloride) [55661-38-6]
  • Delivery Days Customer
    10
  • CAS Number
    55661-38-6
  • Certification
    Research Use Only
  • Estimated Purity
    98.22
  • Molecular Formula
    C9H14Cl2N6O2
  • Molecular Weight
    309.15
  • Scientific Description
    Nimustine hydrochloride (ACNU) is the hydrochloride salt form of Nimustine (HY-13703). Nimustine hydrochloride is an alkylating agent, which induces DNA double-strand breaks (DSBs) and inter-strand crosslinks (ICLs), thereby activating the DNA damage response (DDR) signaling pathway. Nimustine hydrochloride activates p38 MAPK/JNK signaling pathway, and exhibits antitumor activity[1][2].
  • SMILES
    O=C(NCC1=CN=C(C)N=C1N)N(CCCl)N=O.[H]Cl
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    41115800