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Niraparib (R-enantiomer) [1038915-58-0]

Niraparib (R-enantiomer) [1038915-58-0]

T12064
TargetMol Chemicals
CAS Number1038915-58-0
Product group Chemicals
Estimated Purity≥98%
Molecular Weight320.39
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Niraparib (R-enantiomer) [1038915-58-0]
  • Delivery Days Customer
    4
  • CAS Number
    1038915-58-0
  • Certification
    Research Use Only
  • Chemical Name
    Niraparib (R-enantiomer)
  • Estimated Purity
    ≥98%
  • Molecular Formula
    C19H20N4O
  • Molecular Weight
    320.39
  • Scientific Description
    Niraparib R-enantiomer (MK 4827 R-enantiomer) is an inhibitor of PARP1(IC50 of 2.4 nM).
  • Shelf life instruction
    3 years
  • SMILES
    NC(=O)c1cccc2cn(nc12)-c1ccc(cc1)[C@H]1CCCNC1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Discovery of 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide (MK-4827): a novel oral poly(ADP-ribose)polymerase (PARP) inhibitor efficacious in BRCA-1 and -2 mutant tumors.
    Read this paper