Niraparib (tosylate hydrate) [1613220-15-7]

MedChem Express

Niraparib (tosylate hydrate) [1613220-15-7]

10

1613220-15-7

Research Use Only

99.97

C26H30N4O5S

510.61

Niraparib (MK-4827) tosylate hydrate is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC50s of 3.8 and 2.1 nM, respectively. Niraparib tosylate hydrate leads to inhibition of repair of DNA damage, activates apoptosis and shows anti-tumor activity[1][2][3].

NC(C1=CC=CC2=CN(C3=CC=C([C@H]4CNCCC4)C=C3)N=C21)=O.O=S(C5=CC=C(C)C=C5)(O)=O.O

2°C to 8°C

12352200