Nirogacestat
HY-15185
CAS Number1290543-63-3
Product group Chemicals
Estimated Purity99.78
Molecular Weight489.64
Overview
- SupplierMedChem Express
- Product NameNirogacestat [1290543-63-3]
- Delivery Days Customer5
- CAS Number1290543-63-3
- CertificationResearch Use Only
- Estimated Purity99.78
- Molecular FormulaC27H41F2N5O
- Molecular Weight489.64
- Scientific DescriptionNirogacestat (PF-3084014) is a reversible, orally bioavailable, noncompetitive, and selective gamma-secretase inhibitor with an IC 50 of 6.2 nM. Inhibition of Notch signaling by Nirogacestat while minimizing gastrointestinal toxicity presents a promising approach for research of Notch receptor-dependent cancers [1] .
- SMILESFC1=C2C(CC[C@H](N[C@@H](CCC)C(NC3=CN(C(C)(C)CNCC(C)(C)C)C=N3)=O)C2)=CC(F)=C1
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
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![Nirogacestat [1290543-63-3]](https://www.targetmol.com/group3/M00/35/61/CgoaEWayHeiEWHA_AAAAAF4aphY107.png)
Product group Chemicals
CAS Number1290543-63-3
Estimated Purity99.77%
Molecular Weight489.64
- SizePrice