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Nitidine (chloride)

HY-N0498
MedChem Express
CAS Number13063-04-2
Product group Chemicals
Estimated Purity99.75
Molecular Weight383.82
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Nitidine (chloride) [13063-04-2]
  • Delivery Days Customer
    9
  • CAS Number
    13063-04-2
  • Certification
    Research Use Only
  • Estimated Purity
    99.75
  • Molecular Formula
    C21H18ClNO4
  • Molecular Weight
    383.82
  • Scientific Description
    Nitidine chloride, a potential anti-malarial lead compound derived from Zanthoxylum nitidum (Roxb) DC, exerts potent anticancer activity through diverse pathways, including inducing apoptosis , inhibiting STAT3 signaling cascade, DNA topoisomerase 1 and 2A , ERK and c-Src/FAK associated signaling pathway, also has anti-inflammatory activity. Nitidine chloride inhibits LPS-induced inflammatory cytokines production via MAPK and NF-kB pathway [1] [2] [3] [4] [5] .
  • SMILES
    C[N+]1=CC2=CC(OC)=C(OC)C=C2C(C=CC3=C4)=C1C3=CC5=C4OCO5.[Cl-]
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200