Nitrocefin

MedChem Express

Nitrocefin [41906-86-9]

10

41906-86-9

Research Use Only

92.27

C21H16N4O8S2

516.50

Nitrocefin is a highly activated, chromogenic cephalosporin derivative. Nitrocefin is a chromogenic beta-lactamase substrate. Nitrocefin undergoes a distinctive color change from yellow to red as the amide bond in the beta-lactam ring is hydrolyzed by beta-lactamase. Nitrocefin is used in competitive inhibition studies in developmental work on beta-lactamase-resistant antibiotics [1] [2] [3] [4] .

O=C(C(N12)=C(/C=C/C3=CC=C([N+]([O-])=O)C=C3[N+]([O-])=O)CS[C@]2([H])[C@H](NC(CC4=CC=CS4)=O)C1=O)O

-20°C,2°C to 8°C

12352200