WB analysis of various samples using GTX02689 NKX2.8 antibody [NKX28/3233R]. Lane 1 : PC3 whole cell lysate Lane 2 : MCF-7 whole cell lysate
WB analysis of various samples using GTX02689 NKX2.8 antibody [NKX28/3233R]. Lane 1 : PC3 whole cell lysate Lane 2 : MCF-7 whole cell lysate
NKX2.8 antibody [NKX28/3233R]
GTX02689
Overview
- SupplierGeneTex
- Product NameNKX2.8 antibody [NKX28/3233R]
- Delivery Days Customer9
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDNKX28/3233R
- Concentration200 ug/ml
- ConjugateUnconjugated
- Gene ID26257
- Target nameNKX2-8
- Target descriptionNK2 homeobox 8
- Target synonymshomeobox protein NK-2 homolog H; homeobox protein Nkx-2.8; NK-2 homolog 8; NK-2 homolog H; NK2 transcription factor related, locus 8; NKX2.8; Nkx2-9; NKX2H
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects. [provided by RefSeq, Dec 2015]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203