NKX2.8(NKX28/3233R), CF594 conjugate, 0.1mg/mL [26628-22-8]

Biotium

NKX2.8(NKX28/3233R), CF594 conjugate, 0.1mg/mL

9

Western Blot

Research Use Only

Monoclonal

NKX28/3233R

0.1 mg/ml

Other Conjugate

NKX2-8

NK2 homeobox 8

homeobox protein NK-2 homolog H; homeobox protein Nkx-2.8; NK-2 homolog 8; NK-2 homolog H; NK2 transcription factor related, locus 8; NKX2.8; Nkx2-9; NKX2H

Rabbit

IgG

Homeobox protein Nkx-2.8

The protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Animal

Human

2°C to 8°C

12352203