NLRP13 antibody

GeneTex

NLRP13 antibody

9

WB: 1 microg/mL. ICC/IF: 2.5 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

NLRP13

NLR family pyrin domain containing 13

CLR19.7, NALP13, NOD14, PAN13, NACHT, LRR and PYD domains-containing protein 13, NACHT, LRR and PYD containing protein 13, NACHT, leucine rich repeat and PYD containing 13, nucleotide-binding oligomerization domain protein 14, nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 13

Rabbit

IgG

NACHT, LRR and PYD domains-containing protein 13

NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP13, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM, Mar 2008]

Human

-20°C or -80°C,2°C to 8°C

12352203