NLRP3-IN-13 [1704638-35-6]

MedChem Express

NLRP3-IN-13 [1704638-35-6]

10

1704638-35-6

Research Use Only

98.03

C19H15N3O3S

365.41

NLRP3-IN-13 (Compound C77 in reference patent) is a selective and potent NLRP3 inhibitor (IC50: 2.1 microM). NLRP3-IN-13 inhibits NLRP3 andNLRC4 inflammasomes, and inhibits NLRP3-mediated IL-1beta production. NLRP3-IN-13 also inhibits NLRP3 ATPase activity. NLRP3-IN-13 can be used in the research of neuroinflammatory disorders[1].

O=C1OC2=C(N1CC(NCC3=CN=CC(C4=CSC=C4)=C3)=O)C=CC=C2

2°C to 8°C

12131703