NMDAR/HDAC-IN-1

MedChem Express

NMDAR/HDAC-IN-1

10

Research Use Only

C22H28N2O3

368.47

NMDAR/HDAC-IN-1 (Compound 9d) is a dual NMDAR and HDAC inhibitor with a Ki of 0.59 microM for NMDAR and IC50 values of 2.67, 8.00, 2.21, 0.18 and 0.62 microM for HDAC1, HDAC2, HDAC3, HDAC6 and HDAC8, respectively. NMDAR/HDAC-IN-1 efficiently penetrates the blood brain barrier[1].

CC12CC3CC(C1)(CC(C3)(C2)NC(/C=C/C4=CC=C(C=C4)C(NO)=O)=O)C

12131703