NMK-TD-100 [1252802-38-2]

MedChem Express

NMK-TD-100 [1252802-38-2]

5

1252802-38-2

Research Use Only

C19H17N3O3S

367.42

NMK-TD-100 is a modulator for microtubule. NMK-TD-100 binds to tubulin, inhibits the tubulin polymerization with an IC50 of 17.5 microM, inhibits mitosis, and decreases mitochondrial membrane potential (MMP). NMK-TD-100 inhibits the proliferation of HeLa with an IC50 of 1.42 microM, arrests cell cycle at G2/M phase, induces apoptosis in HeLa[1].

COC1=C(C(OC)=CC(C2=NN=C(S2)C3=CNC4=C3C=CC=C4)=C1)OC

12352200