NMNAT1 Antibody

Cusabio

NMNAT1 Antibody

20

ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

NMNAT1

nicotinamide nucleotide adenylyltransferase 1

LCA9, NMNAT, PNAT1, SHILCA, nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1, NMN adenylyltransferase 1, NMN/NaMN adenylyltransferase 1, NaMN adenylyltransferase 1, nicotinamide mononucleotide adenylyltransferase 1, nicotinate-nucleotide adenylyltransferase 1, pyridine nucleotide adenylyltransferase 1

Rabbit

IgG

Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1

Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate (TrMP) as substrate. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity, prefers NAD(+) and NaAD as substrates and degrades NADH, nicotinic acid adenine dinucleotide phosphate (NHD) and nicotinamide guanine dinucleotide (NGD) less effectively. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NaADP(+). Protects against axonal degeneration following mechanical or toxic insults.

Human

-20°C or -80°C

41116161