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NMS-P118

M5270
AbMole BioScience
CAS Number1262417-51-5
DownloadDatasheet
Product group Chemicals
Estimated Purity>99.0%
Molecular Weight395.42
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    NMS-P118
  • Delivery Days Customer
    9
  • CAS Number
    1262417-51-5
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Estimated Purity
    >99.0%
  • Molecular Formula
    C20H24F3N3O2
  • Molecular Weight
    395.42
  • Scientific Description
    NMS-P118 is a potent, orally available, and highly selective PARP-1 inhibitor endowed with excellent ADME and pharmacokinetic profiles, showing 150-fold selectivity for PARP-1 over PARP-2 (Kd 0.009 uM vs 1.39 uM, respectively).
  • SMILES
    NC(=O)C1=CC(=CC2=C1C(=O)N(C2)C3CCN(CC3)C4CCC(F)(F)CC4)F
  • UNSPSC
    12352200

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