NNC 55-0396
ORB1146465
CAS Number357400-13-6
Product group Chemicals
Molecular Weight564.5619
Overview
- SupplierBiorbyt
- Product NameNNC 55-0396 [357400-13-6]
- Delivery Days Customer10
- CAS Number357400-13-6
- CertificationResearch Use Only
- Molecular FormulaC30H40Cl2FN3O2
- Molecular Weight564.5619
- Scientific DescriptionNNC 55-0396, Mibefradil derivative, is a highly selective T-type calcium channel blocker; displays IC50 values of 6.8 and > 100 microM for inhibition of Cav3.1 T-type channels and HVA currents respectively in INS-1 cells. IC50 value: 6.8 nMTarget: Cav3.1 T-type channelNNC 55-0396 can be an essential tool in preventing human ovarian cancer cell proliferation as a result of its ability to inhibit the function of T-type Ca2+ channels. It is believed that NNC 55-0396 may functions by dissolving in or passing through the plasma membrane of cells.
- SMILESC=NN
- UNSPSC12352200
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