NNRT-IN-2 [2999794-78-2]

TargetMol Chemicals

NNRT-IN-2 [2999794-78-2]

16

Research Use Only

C19H14F3N5O3

417.34

NNRT-IN-2 (compound 7w) is an orally administered non-nucleoside reverse transcriptase inhibitor (NNRTI) that effectively suppresses both wild-type HIV-1 and various mutant strains. It inhibits HIV-1 reverse transcriptase with an EC 50 value of 22 nM. Additionally, NNRT-IN-2 exhibits insensitivity to CYP and hERG, demonstrating favorable safety and pharmacokinetic profiles [1].

O(C1=C(C(F)(F)F)C=CN(CC=2N(C)C(=O)NN2)C1=O)C=3C4=C(C=CC3)C=NC=C4

-20°C

51202000