Nociceptin Receptor antibody

GeneTex

Nociceptin Receptor antibody

9

WB: 1:500-2000. IHC-P: 1:400-800. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.5 mg/ml

Unconjugated

OPRL1

opioid related nociceptin receptor 1

kappa3-related opioid receptor; kappa-type 3 opioid receptor; KOR3; KOR-3; nociceptin receptor; nociceptin/orphanin FQ receptor; NOCIR; NOP; NOPr; OOR; opiate receptor-like 1; OPRL; ORL1; orphanin FQ receptor; PNOCR

Rabbit

IgG

Nociceptin receptor

The protein encoded by this gene is a member of the 7 transmembrane-spanning G protein-coupled receptor family, and functions as a receptor for the endogenous, opioid-related neuropeptide, nociceptin/orphanin FQ. This receptor-ligand system modulates a variety of biological functions and neurobehavior, including stress responses and anxiety behavior, learning and memory, locomotor activity, and inflammatory and immune responses. A promoter region between this gene and the 5-adjacent RGS19 (regulator of G-protein signaling 19) gene on the opposite strand functions bi-directionally as a core-promoter for both genes, suggesting co-operative transcriptional regulation of these two functionally related genes. Alternatively spliced transcript variants have been described for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2017]

Human, Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203