Nogo-B-IN-1

MedChem Express

Nogo-B-IN-1

999

Research Use Only

C29H27Cl3N2O6

605.89

Nogo-B-IN-1 ((S,R)-4v) is a covalent Nogo-B inhibitor. Nogo-B-IN-1 inhibits the progression of osteosarcoma (OS) by suppressing Nogo-B activity and the PI3K/AKT/NF-kappaB/Bcl-2 signaling pathway. Nogo-B-IN-1 inhibits the proliferation of OS 143B cells (IC50 = 0.28 microM) and induces apoptosis. Nogo-B-IN-1 can be used for OS targeting research[1].

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