NOL3 peptide

GeneTex

NOL3 peptide

9

The peptide is used for blocking the activity of GTX22002. Incubatingthe peptide with equal volume of antibody for 30 min at 37C usually completely blocks theantibody activity in Western blotting.

Neutralisation/Blocking

Research Use Only

0.20 mg/ml

Unconjugated

Nucleolar protein 30 (Nop30) is coded by the Arc gene. The nuclear isoform of Nop30 (1/Nop30)may be involved in RNA splicing and the cytoplasmic isoform (2/Myp) may inhibit apoptosis. Isoform 1 oligomerizes and binds to SFRS9/SRp30C and also interacts with NPM1. Isoform 2 binds caspase 2, caspase 8 and CED3 and inhibits caspase 8 activity. Nop30 isoform 1 is found in nucleoli and nucleoplasm. Nop30 isoform 2 is cytoplasmic. Nop30 is highly expressed in heart and skeletal muscle with lower levels detected in placenta, liver, kidney and pancreas

-20°C

12352202