Norharmane [244-63-3]

MedChem Express

Norharmane [244-63-3]

9

244-63-3

Research Use Only

99.93

C11H8N2

168.20

Norharmane (Norharman), a beta-carboline alkaloid, is a potent and reversible monoamine oxidase inhibitor, with IC50 values of 6.5 and 4.7 microM for MAO-A and MAO-B, respectively. Norharmane causes antidepressant responses. Norharmane is also a prospective anti-cancer photosensitizer. Norharmane alters polar auxin transport (PAT) by inhibiting PIN2, PIN3 and PIN7 transport proteins, thus causing a significant inhibitory effect on the growth of Arabidopsis thaliana seedlings[1][2][3][4][5][6].

N1C2=C(C=CC=C2)C2=C1C=NC=C2

-20°C,2°C to 8°C

12352200