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Norrin, Human

HY-P79124
MedChem Express
Protein IDQ00604
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Norrin, Human
  • Delivery Days Customer
    5
  • Certification
    Research Use Only
  • Estimated Purity
    96.0
  • Gene ID4693
  • Target name
    NDP
  • Target description
    norrin cystine knot growth factor NDP
  • Target synonyms
    EVR2; FEVR; ND; NDP, norrin cystine knot growth factor; Norrie disease (pseudoglioma); norrie disease protein; norrin; X-linked exudative vitreoretinopathy 2 protein
  • Protein IDQ00604
  • Protein Name
    Norrin
  • Scientific Description
    Norrin protein activates canonical Wnt signaling by binding to FZD4 and LRP5, promotes retinal vascularization and stabilizes beta-catenin (CTNNB1). It cooperates with TSPAN12 to independently activate FZD4, suggesting a Wnt-independent mechanism. Norrin Protein, Human is the recombinant human-derived Norrin protein, expressed by E. coli , with tag free.
  • Storage Instruction
    -20°C
  • UNSPSC
    41116100

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