Notch1/CSL Luciferase Reporter HEK293 Cell Line
60652
Product group (Cell) Culture
Overview
- SupplierBPS Bioscience
- Product NameNotch1/CSL Luciferase Reporter HEK293 Cell Line
- Delivery Days Customer7
- CertificationResearch Use Only
- Scientific DescriptionThe Notch CSL Reporter - HEK293 cell line contains the firefly luciferase gene under the control of Notch-response elements (CSL responsive elements) alone with expression construct for Notch1 E (NOTCH1 that has a deletion of the entire extracellular domain) stably integrated into HEK293 cells. Inside the cells, the Notch1 E can be cleaved by gamma-secretase. The active Notch1 NICD is released to nucleus and induces the constitutive expression of luciferase reporter. The cell line is validated for the inhibition of the expression of luciferase reporter using a known inhibitor of the Notch signaling pathway.
- Storage InstructionLiquid Nitrogen
- UNSPSC12352207