IHC-P analysis of human hippocampus using GTX89476 NOTCH3 antibody, C-term. Antigen retrieval : citrate buffer pH 6 Dilution : 4microg/ml
IHC-P analysis of human hippocampus using GTX89476 NOTCH3 antibody, C-term. Antigen retrieval : citrate buffer pH 6 Dilution : 4microg/ml
NOTCH3 antibody, C-term
GTX89476
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetNOTCH3
Overview
- SupplierGeneTex
- Product NameNOTCH3 antibody, C-term
- Delivery Days Customer9
- Application Supplier NoteIHC-P: 5microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.50 mg/ml
- ConjugateUnconjugated
- Gene ID4854
- Target nameNOTCH3
- Target descriptionnotch receptor 3
- Target synonymsCADASIL; CADASIL1; CASIL; IMF2; LMNS; neurogenic locus notch homolog protein 3; notch 3; Notch homolog 3
- HostGoat
- IsotypeIgG
- Protein IDQ9UM47
- Protein NameNeurogenic locus notch homolog protein 3
- Scientific DescriptionThis gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203