
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA586591(NOTCH3 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200)
NOTCH3 Antibody
CSB-PA586591
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
TargetNOTCH3
Overview
- SupplierCusabio
- Product NameNOTCH3 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID4854
- Target nameNOTCH3
- Target descriptionnotch receptor 3
- Target synonymsCADASIL; CADASIL1; CASIL; IMF2; LMNS; neurogenic locus notch homolog protein 3; notch 3; Notch homolog 3
- HostRabbit
- IsotypeIgG
- Protein IDQ9UM47
- Protein NameNeurogenic locus notch homolog protein 3
- Scientific DescriptionThis gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).
- Storage Instruction-20°C or -80°C
- UNSPSC12352203