NOX1 antibody
GTX103888
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetNOX1
Overview
- SupplierGeneTex
- Product NameNOX1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.14 mg/ml
- ConjugateUnconjugated
- Gene ID27035
- Target nameNOX1
- Target descriptionNADPH oxidase 1
- Target synonymsGP91-2; mitogenic oxidase (pyridine nucleotide-dependent superoxide-generating); mitogenic oxidase 1; MOX1; NADH/NADPH mitogenic oxidase subunit P65-MOX; NADPH oxidase 1; NADPH oxidase homolog-1; NOH1; NOH-1
- HostRabbit
- IsotypeIgG
- Protein IDQ9Y5S8
- Protein NameNADPH oxidase 1
- Scientific DescriptionVoltage-gated proton (hydrogen) channels play an important role in cellular defense against acidic stress. They are unique among ion channels with respect to their extremely high selectivity, marked temperature dependence, and unitary conductance, which is 3 orders of magnitude lower than that of most other ion channels. NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Cyba and Nox2 mutant rats show different incidences of eosinophilia in the genetic background- and sex-dependent manner.Read more
- Osteopontin promotes hepatocellular carcinoma progression through inducing JAK2/STAT3/NOX1-mediated ROS production. Wu Q et al., 2022 Apr 13, Cell Death DisRead more
- Protein Kinase CK2 Acts as a Molecular Brake to Control NADPH Oxidase 1 Activation and Colon Inflammation. Liu D et al., 2022, Cell Mol Gastroenterol HepatolRead more
- Pharmacological Activation Of Aldehyde Dehydrogenase 2 Protects Against Heatstroke-Induced Acute Lung Injury by Modulating Oxidative Stress and Endothelial Dysfunction. Tsai HY et al., 2021, Front ImmunolRead more
- Intercellular Adhesion Molecule-1-Induced Posttraumatic Brain Injury Neuropathology in the Prefrontal Cortex and Hippocampus Leads to Sensorimotor Function Deficits and Psychological Stress. Bhowmick S et al., 2021 Jul-Aug, eNeuroRead more
- DDX19A Promotes Metastasis of Cervical Squamous Cell Carcinoma by Inducing NOX1-Mediated ROS Production. Jiang Y et al., 2021, Front OncolRead more
- Protective effects of valsartan administration on doxorubicin-induced myocardial injury in rats and the role of oxidative stress and NOX2/NOX4 signaling. Cheng D et al., 2020 Nov, Mol Med RepRead more
- KRIT1 loss-mediated upregulation of NOX1 in stromal cells promotes paracrine pro-angiogenic responses. Finetti F et al., 2020 Apr, Cell SignalRead more
- Upregulated NOX1 expression in gallbladder cancer-associated fibroblasts predicts a poor prognosis. Wang FT et al., 2019 Oct, Oncol RepRead more
- Renoprotective effects of brown adipose tissue activation in diabetic mice. Cai YY et al., 2019 Apr 24, J DiabetesRead more