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NOX1 antibody

GTX103888
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetNOX1
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Overview

  • Supplier
    GeneTex
  • Product Name
    NOX1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.14 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID27035
  • Target name
    NOX1
  • Target description
    NADPH oxidase 1
  • Target synonyms
    GP91-2; mitogenic oxidase (pyridine nucleotide-dependent superoxide-generating); mitogenic oxidase 1; MOX1; NADH/NADPH mitogenic oxidase subunit P65-MOX; NADPH oxidase 1; NADPH oxidase homolog-1; NOH1; NOH-1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9Y5S8
  • Protein Name
    NADPH oxidase 1
  • Scientific Description
    Voltage-gated proton (hydrogen) channels play an important role in cellular defense against acidic stress. They are unique among ion channels with respect to their extremely high selectivity, marked temperature dependence, and unitary conductance, which is 3 orders of magnitude lower than that of most other ion channels. NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Cyba and Nox2 mutant rats show different incidences of eosinophilia in the genetic background- and sex-dependent manner.
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  • Osteopontin promotes hepatocellular carcinoma progression through inducing JAK2/STAT3/NOX1-mediated ROS production. Wu Q et al., 2022 Apr 13, Cell Death Dis
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  • Protein Kinase CK2 Acts as a Molecular Brake to Control NADPH Oxidase 1 Activation and Colon Inflammation. Liu D et al., 2022, Cell Mol Gastroenterol Hepatol
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  • Pharmacological Activation Of Aldehyde Dehydrogenase 2 Protects Against Heatstroke-Induced Acute Lung Injury by Modulating Oxidative Stress and Endothelial Dysfunction. Tsai HY et al., 2021, Front Immunol
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  • Intercellular Adhesion Molecule-1-Induced Posttraumatic Brain Injury Neuropathology in the Prefrontal Cortex and Hippocampus Leads to Sensorimotor Function Deficits and Psychological Stress. Bhowmick S et al., 2021 Jul-Aug, eNeuro
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  • DDX19A Promotes Metastasis of Cervical Squamous Cell Carcinoma by Inducing NOX1-Mediated ROS Production. Jiang Y et al., 2021, Front Oncol
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  • Protective effects of valsartan administration on doxorubicin-induced myocardial injury in rats and the role of oxidative stress and NOX2/NOX4 signaling. Cheng D et al., 2020 Nov, Mol Med Rep
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  • KRIT1 loss-mediated upregulation of NOX1 in stromal cells promotes paracrine pro-angiogenic responses. Finetti F et al., 2020 Apr, Cell Signal
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  • Upregulated NOX1 expression in gallbladder cancer-associated fibroblasts predicts a poor prognosis. Wang FT et al., 2019 Oct, Oncol Rep
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  • Renoprotective effects of brown adipose tissue activation in diabetic mice. Cai YY et al., 2019 Apr 24, J Diabetes
    Read more