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NOX1 antibody

GTX103888
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetNOX1
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Overview

  • Supplier
    GeneTex
  • Product Name
    NOX1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.14 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID27035
  • Target name
    NOX1
  • Target description
    NADPH oxidase 1
  • Target synonyms
    GP91-2, MOX1, NOH-1, NOH-1L, NOH1, NADPH oxidase 1, NADH/NADPH mitogenic oxidase subunit P65-MOX, NADPH oxidase homolog-1, mitogenic oxidase (pyridine nucleotide-dependent superoxide-generating), mitogenic oxidase 1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9Y5S8
  • Protein Name
    NADPH oxidase 1
  • Scientific Description
    Voltage-gated proton (hydrogen) channels play an important role in cellular defense against acidic stress. They are unique among ion channels with respect to their extremely high selectivity, marked temperature dependence, and unitary conductance, which is 3 orders of magnitude lower than that of most other ion channels. NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Mori M, Dai J, Miyahara H, et al. Cyba and Nox2 mutant rats show different incidences of eosinophilia in the genetic background- and sex-dependent manner. Exp Anim. 2023,72(2):233-241. doi: 10.1538/expanim.22-0122
    Read this paper
  • Wu Q, Li L, Miao C, et al. Osteopontin promotes hepatocellular carcinoma progression through inducing JAK2/STAT3/NOX1-mediated ROS production. Cell Death Dis. 2022,13(4):341. doi: 10.1038/s41419-022-04806-9
    Read this paper
  • Liu D, Marie JC, Pelletier AL, et al. Protein Kinase CK2 Acts as a Molecular Brake to Control NADPH Oxidase 1 Activation and Colon Inflammation. Cell Mol Gastroenterol Hepatol. 2022,13(4):1073-1093. doi: 10.1016/j.jcmgh.2022.01.003
    Read this paper
  • Tsai HY, Hsu YJ, Lu CY, et al. Pharmacological Activation Of Aldehyde Dehydrogenase 2 Protects Against Heatstroke-Induced Acute Lung Injury by Modulating Oxidative Stress and Endothelial Dysfunction. Front Immunol. 2021,12:740562. doi: 10.3389/fimmu.2021.740562
    Read this paper
  • Bhowmick S, Malat A, Caruso D, et al. Intercellular Adhesion Molecule-1-Induced Posttraumatic Brain Injury Neuropathology in the Prefrontal Cortex and Hippocampus Leads to Sensorimotor Function Deficits and Psychological Stress. eNeuro. 2021,8(4):pii: ENEURO.0242-21.2021. doi: 10.1523/ENEURO.0242-21.2021.
    Read this paper
  • Jiang Y, Wang B, Li Y, et al. DDX19A Promotes Metastasis of Cervical Squamous Cell Carcinoma by Inducing NOX1-Mediated ROS Production. Front Oncol. 2021,11:629974. doi: 10.3389/fonc.2021.629974
    Read this paper
  • Cheng D, Chen L, Tu W, et al. Protective effects of valsartan administration on doxorubicin‑induced myocardial injury in rats and the role of oxidative stress and NOX2/NOX4 signaling. Mol Med Rep. 2020,22(5):4151-4162. doi: 10.3892/mmr.2020.11521
    Read this paper
  • Finetti F, Schiavo I, Ercoli J, et al. KRIT1 loss-mediated upregulation of NOX1 in stromal cells promotes paracrine pro-angiogenic responses. Cell Signal. 2020,68:109527. doi: 10.1016/j.cellsig.2020.109527
    Read this paper
  • Wang FT, Hassan M, Ansari KH, et al. Upregulated NOX1 expression in gallbladder cancer‑associated fibroblasts predicts a poor prognosis. Oncol Rep. 2019,42(4):1475-1486. doi: 10.3892/or.2019.7249
    Read this paper
  • Cai YY, Zhang HB, Fan CX, et al. Renoprotective effects of brown adipose tissue activation in diabetic mice. J Diabetes. 2019,11(12):958-970. doi: 10.1111/1753-0407.12938
    Read this paper