Bio-Connect

NOX2 / gp91phox antibody [NL7]

GTX80329
GeneTex
TargetCYBB
Product group Antibodies
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Overview

  • Supplier
    GeneTex
  • Product Name
    NOX2 / gp91phox antibody [NL7]
  • Delivery Days Customer
    9
  • Antibody Specificity
    Human NOX2/gp91phox - 498-EKDVITGRKQ-507
  • Application Supplier Note
    Recommended Starting Dilutions:For WB: Use at 1:1000Optimal dilutions should be determined experimentally by the researcher.
  • Clone ID
    NL7
  • Concentration
    1 mg/ml
  • Formulation
    Liquid
  • Gene ID1536
  • Target name
    CYBB
  • Target description
    cytochrome b-245 beta chain
  • Target synonyms
    AMCBX2; CGD; CGD91-phox; CGDX; cytochrome b(558) subunit beta; cytochrome b-245 beta polypeptide; cytochrome b-245 heavy chain; cytochrome b558 subunit beta; GP91-1; GP91PHOX; GP91-PHOX; heme-binding membrane glycoprotein gp91phox; IMD34; NADPH oxidase 2; neutrophil cytochrome b 91 kDa polypeptide; NOX2; p22 phagocyte B-cytochrome; p91-PHOX; superoxide-generating NADPH oxidase heavy chain subunit
  • Protein IDP04839
  • Protein Name
    Cytochrome b-245 heavy chain
  • Scientific Description
    Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cells respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. [provided by RefSeq, Jul 2008]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203