NP3-562 [2409825-32-5]

TargetMol Chemicals

NP3-562 [2409825-32-5]

16

Research Use Only

C19H24ClN5O3S

437.94

NP3-562 is a powerful, orally administered tricyclic NLRP3 inhibitor, demonstrating an IC50 of 214 nM. At a dosage of 30 mg/kg given orally (p.o.), NP3-562 effectively suppresses IL-1beta release in a mouse model of acute peritonitis [1].

C(C)(C)(O)C=1N2C3=C(C=C2C(=O)N(CC(N[C@H]4CN(C)CCC4)=O)N1)SC(Cl)=C3

-20°C

12352200