NPD926 [384361-79-9]

MedChem Express

NPD926 [384361-79-9]

5

384361-79-9

Research Use Only

C29H35ClN2O2

479.05

NPD926 is a small molecule that targets glutathione and induces cancer cell death. The Xc- system and glutathione are therapeutic targets in cancer. NPD926 causes cellular glutathione depletion and subsequent generation of reactive oxygen species (ROS), thereby sensitizing fibroblasts to Xc- system inhibitors. NPD926 is a ROS inducer with anticancer activity.[1].

CC(OC1=CC=C(C=C1)C(C2=CC=CC=C2)CCN(CC3=CC=C(C=C3)N(C)C)C(CCl)=O)C

12352200