NPL Antibody

Cusabio

NPL Antibody

20

ImmunoFluorescence, Western Blot, ELISA

Research Use Only

Polyclonal

Unconjugated

NPL

N-acetylneuraminate pyruvate lyase

C112, C1orf13, NAL, NPL1, N-acetylneuraminate lyase, N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase), N-acetylneuraminic acid aldolase, NALase, dihydrodipicolinate synthetase homolog 1, sialate-pyruvate lyase, sialic acid aldolase

Rabbit

IgG

N-acetylneuraminate lyase

Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate. It prevents sialic acids from being recycled and returning to the cell surface. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway. Although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded (By similarity).

Human, Mouse

-20°C or -80°C

41116161