Western Blot Positive WB detected in: U87 whole cell lysate All lanes: NPRL3 antibody at 2.7microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 64 kDa Observed band size: 64 kDa
Western Blot Positive WB detected in: U87 whole cell lysate All lanes: NPRL3 antibody at 2.7microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 64 kDa Observed band size: 64 kDa
NPRL3 Antibody
CSB-PA619643LA01HU
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetNPRL3
Overview
- SupplierCusabio
- Product NameNPRL3 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID8131
- Target nameNPRL3
- Target descriptionNPR3 like, GATOR1 complex subunit
- Target synonymsC16orf35, CGTHBA, FFEVF3, HS-40, MARE, NPR3, RMD11, GATOR1 complex protein NPRL3, -14 gene protein, GATOR complex protein NPRL3, alpha-globin regulatory element-containing gene protein, conserved gene telomeric to alpha globin cluster
- HostRabbit
- IsotypeIgG
- Protein IDQ12980
- Protein NameGATOR1 complex protein NPRL3
- Scientific DescriptionAs a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling. The GATOR1 complex is negatively regulated by GATOR2 the other GATOR subcomplex in this amino acid-sensing branch of the TORC1 pathway.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC41116161
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