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NPS-2143

HY-10007
MedChem Express
CAS Number284035-33-2
DownloadMSDS
Product group Chemicals
Estimated Purity99.34
Molecular Weight408.9205
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Overview

  • Supplier
    MedChem Express
  • Product Name
    NPS-2143 [284035-33-2]
  • Delivery Days Customer
    10
  • CAS Number
    284035-33-2
  • Certification
    Research Use Only
  • Estimated Purity
    99.34
  • Molecular Formula
    C24H25ClN2O2
  • Molecular Weight
    408.9205
  • Scientific Description
    NPS-2143 (SB-262470A), an orally active calcilytic agent, is a selective and potent calcium ion-sensing receptor (CaSR) antagonist. NPS-2143 (SB-262470A) blocks increases in cytoplasmic Ca 2+ concentrations ( IC 50 =43 nM) elicited by activating the Ca 2+ receptor in HEK 293 cells expressing the human Ca 2+ receptor [1] [2] .
  • SMILES
    N#CC1=C(OC[C@@H](CNC(C)(CC2=CC=C3C=CC=CC3=C2)C)O)C=CC=C1Cl
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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