NQTrp

Biorbyt

NQTrp

10

185351-19-3

Research Use Only

C21H16N2O4

360.363

NQTrp, an aromatic naphthoquinone-tryptophan hybrid molecule, an inhibitor of the aggregation of the tau protein with generic anti-amyloidogenic effects. NQTrp inhibits the in vitro aggregation of hexapeptide (41GCWMLY46 within the N-terminus of gammaD-crystallin) as well as full-length gammaD-crystallin.

O=C1C2=C(C=CC=C2)C(=O)C=C1N[C@H](C(O)=O)CC1C2=C(C=CC=C2)NC=1

12352200