NR2E1 Antibody

Cusabio

NR2E1 Antibody

20

Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

NR2E1

nuclear receptor subfamily 2 group E member 1

TLL, TLX, XTLL, nuclear receptor subfamily 2 group E member 1, nuclear receptor TLX, protein tailless homolog, tailes-related receptor, tailless

Rabbit

IgG

Nuclear receptor subfamily 2 group E member 1

Orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half-site sequence 5-AAGGTCA-3 in which the 5 flanking nucleotides participate in determining receptor specificity (By similarity). May be required to pattern anterior brain differentiation. Involved in the regulation of retinal development and essential for vision. During retinogenesis, regulates PTEN-Cyclin D expression via binding to the promoter region of PTEN and suppressing its activity (By similarity). May be involved in retinoic acid receptor (RAR) regulation in retinal cells.

Human, Mouse

-20°C or -80°C

41116161