NR4A2, Human (P.pastoris, His)

MedChem Express

NR4A2, Human (P.pastoris, His)

10

Research Use Only

NR4A2

nuclear receptor subfamily 4 group A member 2

HZF-3, IDLDP, NOT, NURR1, RNR1, TINUR, nuclear receptor subfamily 4 group A member 2, NGFI-B/nur77 beta-type transcription factor homolog, T-cell nuclear receptor NOT, immediate-early response protein NOT, intermediate-early receptor protein, nuclear receptor related 1, nur related protein-1, human homolog of, orphan nuclear receptor NR4A2, orphan nuclear receptor NURR1, transcriptionally inducible nuclear receptor related 1, transcriptionally-inducible nuclear receptor

Nuclear receptor subfamily 4 group A member 2

NR4A2, a crucial transcriptional regulator, is vital for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons. It plays a pivotal role in the expression of key genes (SLC6A3, SLC18A2, TH, DRD2) essential for mdDA neuron development. Interactions with SFPQ, NCOR2, SIN3A, HADC1, and PER2 contribute to its regulatory functions in mdDA neuron development, with the NCOR2 interaction influenced by the absence of PITX3. NR4A2 Protein, Human (P.pastoris, His) is the recombinant human-derived NR4A2 protein, expressed by P. pastoris , with N-His labeled tag.

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