IHC-P analysis of human breast adenocarcinoma tissue using GTX84007 NRBP1 antibody [5C3]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.
![IHC-P analysis of human ovary adenocarcinoma tissue using GTX84007 NRBP1 antibody [5C3]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX84007/GTX84007_2139_IHC-P_w_23061420_309.webp "IHC-P analysis of human ovary adenocarcinoma tissue using GTX84007 NRBP1 antibody [5C3]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human pancreas carcinoma tissue using GTX84007 NRBP1 antibody [5C3]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX84007/GTX84007_2140_IHC-P_w_23061420_607.webp "IHC-P analysis of human pancreas carcinoma tissue using GTX84007 NRBP1 antibody [5C3]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human thyroid carcinoma tissue using GTX84007 NRBP1 antibody [5C3]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX84007/GTX84007_2141_IHC-P_w_23061420_768.webp "IHC-P analysis of human thyroid carcinoma tissue using GTX84007 NRBP1 antibody [5C3]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human breast tissue using GTX84007 NRBP1 antibody [5C3]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX84007/GTX84007_2142_IHC-P_w_23061420_256.webp "IHC-P analysis of human breast tissue using GTX84007 NRBP1 antibody [5C3]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human colon tissue using GTX84007 NRBP1 antibody [5C3]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX84007/GTX84007_2143_IHC-P_w_23061420_982.webp "IHC-P analysis of human colon tissue using GTX84007 NRBP1 antibody [5C3]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human lymphoma tissue using GTX84007 NRBP1 antibody [5C3]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX84007/GTX84007_2144_IHC-P_w_23061420_142.webp "IHC-P analysis of human lymphoma tissue using GTX84007 NRBP1 antibody [5C3]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human ovary tissue using GTX84007 NRBP1 antibody [5C3]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX84007/GTX84007_2145_IHC-P_w_23061420_328.webp "IHC-P analysis of human ovary tissue using GTX84007 NRBP1 antibody [5C3]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human pancreas tissue using GTX84007 NRBP1 antibody [5C3]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX84007/GTX84007_2146_IHC-P_w_23061420_966.webp "IHC-P analysis of human pancreas tissue using GTX84007 NRBP1 antibody [5C3]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![FACS analysis of HEK293T cells transfected with either NRBP1 plasmid(Red) or empty vector control plasmid(Blue) using GTX84007 NRBP1 antibody [5C3].](https://www.genetex.com/upload/website/prouct_img/normal/GTX84007/GTX84007_273_FACS_w_23061420_743.webp "FACS analysis of HEK293T cells transfected with either NRBP1 plasmid(Red) or empty vector control plasmid(Blue) using GTX84007 NRBP1 antibody [5C3].")
IHC-P analysis of human breast adenocarcinoma tissue using GTX84007 NRBP1 antibody [5C3]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.
NRBP1 antibody [5C3]
GTX84007
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetNRBP1
Overview
- SupplierGeneTex
- Product NameNRBP1 antibody [5C3]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:2000. ICC/IF: 1:100. IHC-P: 1:50. FACS: 1:100. IP: 2ug/500ul. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID5C3
- Concentration1.48 mg/ml
- ConjugateUnconjugated
- Gene ID29959
- Target nameNRBP1
- Target descriptionnuclear receptor binding protein 1
- Target synonymsBCON3, MADM, MUDPNP, NRBP, nuclear receptor-binding protein, multiple domain putative nuclear protein, myeloid leukemia factor 1 adaptor molecule
- HostMouse
- IsotypeIgG2b
- Protein IDQ9UHY1
- Protein NameNuclear receptor-binding protein
- Scientific DescriptionMay play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases. Binding to the NS3 protein of dengue virus type 2 appears to subvert this activity into the alteration of the intracellular membrane structure associated with flaviviral replication.
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Yang X, Cruz MI, Nguyen EV, et al. The pseudokinase NRBP1 activates Rac1/Cdc42 via P-Rex1 to drive oncogenic signalling in triple-negative breast cancer. Oncogene. 2023,42(11):833-847. doi: 10.1038/s41388-023-02594-wRead this paper
- Yang C, Zhang X, Gao C, et al. NRBP1 negatively regulates SALL4 to reduce the invasion and migration, promote apoptosis and increase the sensitivity to chemotherapy drugs of breast cancer cells. Oncol Lett. 2022,23(4):139. doi: 10.3892/ol.2022.13259Read this paper
- Wei H, Wang H, Ji Q, et al. NRBP1 is downregulated in breast cancer and NRBP1 overexpression inhibits cancer cell proliferation through Wnt/β-catenin signaling pathway. Onco Targets Ther. 2015,8:3721-30. doi: 10.2147/OTT.S89779Read this paper
Datasheet
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