IHC-P analysis of human breast adenocarcinoma tissue using GTX84007 NRBP1 antibody [5C3]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.
![IHC-P analysis of human ovary adenocarcinoma tissue using GTX84007 NRBP1 antibody [5C3]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX84007/GTX84007_2139_IHC-P_w_23061420_309.webp "IHC-P analysis of human ovary adenocarcinoma tissue using GTX84007 NRBP1 antibody [5C3]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human pancreas carcinoma tissue using GTX84007 NRBP1 antibody [5C3]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX84007/GTX84007_2140_IHC-P_w_23061420_607.webp "IHC-P analysis of human pancreas carcinoma tissue using GTX84007 NRBP1 antibody [5C3]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human thyroid carcinoma tissue using GTX84007 NRBP1 antibody [5C3]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX84007/GTX84007_2141_IHC-P_w_23061420_768.webp "IHC-P analysis of human thyroid carcinoma tissue using GTX84007 NRBP1 antibody [5C3]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human breast tissue using GTX84007 NRBP1 antibody [5C3]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX84007/GTX84007_2142_IHC-P_w_23061420_256.webp "IHC-P analysis of human breast tissue using GTX84007 NRBP1 antibody [5C3]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human colon tissue using GTX84007 NRBP1 antibody [5C3]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX84007/GTX84007_2143_IHC-P_w_23061420_982.webp "IHC-P analysis of human colon tissue using GTX84007 NRBP1 antibody [5C3]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human lymphoma tissue using GTX84007 NRBP1 antibody [5C3]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX84007/GTX84007_2144_IHC-P_w_23061420_142.webp "IHC-P analysis of human lymphoma tissue using GTX84007 NRBP1 antibody [5C3]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human ovary tissue using GTX84007 NRBP1 antibody [5C3]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX84007/GTX84007_2145_IHC-P_w_23061420_328.webp "IHC-P analysis of human ovary tissue using GTX84007 NRBP1 antibody [5C3]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human pancreas tissue using GTX84007 NRBP1 antibody [5C3]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX84007/GTX84007_2146_IHC-P_w_23061420_966.webp "IHC-P analysis of human pancreas tissue using GTX84007 NRBP1 antibody [5C3]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![FACS analysis of HEK293T cells transfected with either NRBP1 plasmid(Red) or empty vector control plasmid(Blue) using GTX84007 NRBP1 antibody [5C3].](https://www.genetex.com/upload/website/prouct_img/normal/GTX84007/GTX84007_273_FACS_w_23061420_743.webp "FACS analysis of HEK293T cells transfected with either NRBP1 plasmid(Red) or empty vector control plasmid(Blue) using GTX84007 NRBP1 antibody [5C3].")
IHC-P analysis of human breast adenocarcinoma tissue using GTX84007 NRBP1 antibody [5C3]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.
NRBP1 antibody [5C3]
GTX84007
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetNRBP1
Overview
- SupplierGeneTex
- Product NameNRBP1 antibody [5C3] - Overexpression Validated
- Delivery Days Customer9
- Application Supplier NoteWB: 1:2000. ICC/IF: 1:100. IHC-P: 1:50. FACS: 1:100. IP: 2ug/500ul. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID5C3
- Concentration1.48 mg/ml
- ConjugateUnconjugated
- Gene ID29959
- Target nameNRBP1
- Target descriptionnuclear receptor binding protein 1
- Target synonymsBCON3; MADM; MUDPNP; multiple domain putative nuclear protein; myeloid leukemia factor 1 adaptor molecule; NRBP; nuclear receptor-binding protein
- HostMouse
- IsotypeIgG2b
- Protein IDQ9UHY1
- Protein NameNuclear receptor-binding protein
- Scientific DescriptionMay play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases. Binding to the NS3 protein of dengue virus type 2 appears to subvert this activity into the alteration of the intracellular membrane structure associated with flaviviral replication.
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- The pseudokinase NRBP1 activates Rac1/Cdc42 via P-Rex1 to drive oncogenic signalling in triple-negative breast cancer.Read more
- NRBP1 negatively regulates SALL4 to reduce the invasion and migration, promote apoptosis and increase the sensitivity to chemotherapy drugs of breast cancer cells. Yang C et al., 2022 Apr, Oncol LettRead more
- NRBP1 is downregulated in breast cancer and NRBP1 overexpression inhibits cancer cell proliferation through Wnt/beta-catenin signaling pathway. Wei H et al., 2015, Onco Targets TherRead more
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