Nrf2/HO-1 activator 2

MedChem Express

Nrf2/HO-1 activator 2 [2883506-31-6]

10

Research Use Only

C20H16F2O5

374.33

Nrf2/HO-1 activator 2 (compound 13m), difluoro-substituted derivative, is a potent Nrf2/HO-1 activator. Nrf2/HO-1 activator 2 has neuroprotective and antioxidant effects through the Nrf2/HO-1 pathway mediated by phosphorylation of ERK1/2, JNK, or Akt in PC12 cells. Nrf2/HO-1 activator 2 can be used in the research of Parkinsons disease (PD)[1].

O=C1C(C2=CC=C(F)C=C2F)=COC3=C1C4=C(CC(O)C(C)(C)O4)C(O)=C3

12131703