NRG1 Polyclonal Antibody

Reddot Biotech

NRG1 Polyclonal Antibody

5

Western Blot, ELISA

Research Use Only

Polyclonal

0.8 mg/ml

Unconjugated

NRG1

neuregulin 1

acetylcholine receptor-inducing activity; ARIA; GGF; GGF2; glial growth factor 2; heregulin, alpha (45kD, ERBB2 p185-activator); HGL; HRG; HRG1; HRGA; MST131; MSTP131; NDF; neu differentiation factor; NRG1-IT2; pro-neuregulin-1, membrane-bound isoform; pro-NRG1; sensory and motor neuron derived factor; SMDF

Rabbit

IgG

The protein encoded by this gene was originally identified as a 44-kD glycoprotein that interacts with the NEU/ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. This protein is a signaling protein that mediates cell-cell interactions and plays critical roles in the growth and development of multiple organ systems. It is known that an extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are tissue-specifically expressed and differ significantly in their structure, and thereby these isoforms are classified into types I, II, III, IV, V and VI. The gene dysregulation has been linked to diseases such as cancer, schizophrenia and bipolar disorder (BPD).

-20°C

12352203