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NRIP antibody

GTX105954
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetDCAF6
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Overview

  • Supplier
    GeneTex
  • Product Name
    NRIP antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID55827
  • Target name
    DCAF6
  • Target description
    DDB1 and CUL4 associated factor 6
  • Target synonyms
    1200006M05Rik; androgen receptor complex-associated protein; ARCAP; DDB1- and CUL4-associated factor 6; IQ motif and WD repeat-containing protein 1; IQ motif and WD repeats 1; IQWD1; MSTP055; NRIP; nuclear receptor interaction protein; PC326
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ58WW2
  • Protein Name
    DDB1- and CUL4-associated factor 6
  • Scientific Description
    Ligand-dependent coactivator of nuclear receptors. Enhance transcriptional activity of the nuclear receptors NR3C1 and AR. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Autoantibody of NRIP, a novel AChR-interacting protein, plays a detrimental role in myasthenia gravis. Tsai LK et al., 2021 Jun, J Cachexia Sarcopenia Muscle
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  • NRIP/DCAF6 stabilizes the androgen receptor protein by displacing DDB2 from the CUL4A-DDB1 E3 ligase complex in prostate cancer. Chen HH et al., 2017 Mar 28, Oncotarget
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  • NRIP, a novel calmodulin binding protein, activates calcineurin to dephosphorylate human papillomavirus E2 protein. Chang SW et al., 2011 Jul, J Virol
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