NS3736 [265646-94-4]
HY-164532
CAS Number265646-94-4
Product group Chemicals
Molecular Weight461.62
Overview
- SupplierMedChem Express
- Product NameNS3736 [265646-94-4]
- Delivery Days Customer5
- CAS Number265646-94-4
- CertificationResearch Use Only
- Molecular FormulaC15H9BrClF3N6O
- Molecular Weight461.62
- Scientific DescriptionNS3736 is an orally effective chloride channel inhibitor that can be used for the research of osteoporosis. NS3736 targets the CIC-7 channel in osteocytes, blocks osteoclast acidification and resorption in vitro, with IC50=30 microM. In a rat model of ovariectomy-induced osteoporosis, NS3736 can enhance bone strength and bone density[1].
- SMILESO=C(NC1=C(C2=NN=NN2)C=C(Br)C=C1)NC3=CC=C(C(C(F)(F)F)=C3)Cl
- UNSPSC12352200