NSC339614 (potassium) [1135037-53-4]

MedChem Express

NSC339614 (potassium) [1135037-53-4]

9

1135037-53-4

Research Use Only

C10H4KN3O6S

333.32

NSC339614 potassium is a selective GluN1/GluN2C and GluN1/GluN2D receptor enhancer with the activity of enhancing neuronal responses to specific NMDA receptors. NSC339614 potassium can selectively enhance the signaling of GluN1/GluN2C and GluN1/GluN2D receptors without affecting other NMDA receptors. The mechanism of action of NSC339614 potassium does not compete with agonists of L-glutamate or glycine, nor does it depend on membrane potential. The activity of NSC339614 potassium depends on the specific structure of the agonist ligand binding domain, showing its potential as a novel pharmacological agent for studying the function of NMDA receptor subtypes and providing new lead compounds for a variety of neurological diseases[1].

O=[N+](C1=CC=C2C3=NON=C3C=C(S(=O)(O[K])=O)C2=C1)[O-]

12131703