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NT5C2 antibody [N2C1], Internal

GTX105719
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetNT5C2
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Overview

  • Supplier
    GeneTex
  • Product Name
    NT5C2 antibody [N2C1], Internal
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID22978
  • Target name
    NT5C2
  • Target description
    5'-nucleotidase, cytosolic II
  • Target synonyms
    GMP, NT5B, PNT5, SPG45, SPG65, cN-II, cytosolic purine 5'-nucleotidase, 5'-nucleotidase (purine), cytosolic type B, IMP-specific 5'-NT, cytosolic IMP/GMP-specific 5'-nucleotidase, cytosolic nucleoside phosphotransferase 5'N, epididymis secretory sperm binding protein, high Km 5'-nucleotidase, spastic paraplegia 45 (autosomal recessive)
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    Purine 5-prime-nucleotidase (EC 3.1.3.5) preferentially hydrolyzes inosine 5-prime-monophosphate (IMP) and other purine nucleotides, and is allosterically activated by various compounds, including ATP. The enzyme is exclusively located in the cytoplasmic matrix of cells and may have a critical role in the maintenance of a constant composition of intracellular purine/pyrimidine nucleotides in cooperation with other nucleotidases.[supplied by OMIM]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Chen YT, Lin WD, Liao WL, et al. NT5C2 methylation regulatory interplay between DNMT1 and insulin receptor in type 2 diabetes. Sci Rep. 2020,10(1):16087. doi: 10.1038/s41598-020-71336-9
    Read this paper