NTAN1 antibody [N1C3]

GeneTex

NTAN1 antibody [N1C3]

9

WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

NTAN1

N-terminal asparagine amidase

PNAA; PNAD; protein NH2-terminal asparagine deamidase; protein N-terminal Asn amidase; protein N-terminal asparagine amidase; protein N-terminal asparagine amidohydrolase; protein NTN-amidase

Rabbit

IgG

Protein N-terminal asparagine amidohydrolase

Side-chain deamidation of N-terminal asparagine residues to aspartate. Required for the ubiquitin-dependent turnover of intracellular proteins that initiate with Met-Asn. These proteins are acetylated on the retained initiator methionine and can subsequently be modified by the removal of N-acetyl methionine by acylaminoacid hydrolase (AAH). Conversion of the resulting N-terminal asparagine to aspartate by PNAD renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. This enzyme does not act on substrates with internal or C-terminal asparagines and does not act on glutamine residues in any position.

Human

-20°C or -80°C,2°C to 8°C

12352203