NTPO (trisodium) [7611-50-9]

MedChem Express

NTPO (trisodium) [7611-50-9]

5

7611-50-9

Research Use Only

C3H9NNa3O9P3

365.00

NTPO trisodium is a DNA damage inducer, causing genomic DNA damage and fragmentation, activating ATR-mediated cell cycle checkpoints. The DNA damaging effects of NTPO trisodium are abrogated by base excision repair (BER) but not nucleotide excision repair (NER)[1].

O=P(CN(CP(O)(O[Na])=O)CP(O)(O[Na])=O)(O[Na])O

12352200