Nuciferine [475-83-2]

MedChem Express

Nuciferine [475-83-2]

10

475-83-2

Research Use Only

99.90

C19H21NO2

295.38

Nuciferine is an antagonist at 5-HT2A (IC50=478 nM), 5-HT2C (IC50=131 nM), and 5-HT2B (IC50=1 microM), an inverse agonist at 5-HT7 (IC50=150 nM), a partial agonist at D2 (EC50=64 nM), D5 (EC50=2.6 microM) and 5-HT6 (EC50=700 nM), an agonist at 5-HT1A (EC50=3.2 microM) and D4 (EC50=2 microM) receptor.

CN1CCC2=CC(OC)=C(OC)C3=C2[C@@]1([H])CC4=CC=CC=C34

-20°C,2°C to 8°C

12352200