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Immunohistochemistry analysis of nuclear staining of colon cancer sections using Nucleolin mAb (4E2).
Immunohistochemistry analysis of nuclear staining of colon cancer sections using Nucleolin mAb (4E2).
Immunohistochemistry analysis of nuclear staining of colon cancer sections using Nucleolin mAb (4E2).

Nucleolin antibody [4E2]

Research Use Only
GTX13541
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry
Product group Antibodies
ReactivityBovine, Human
TargetNCL
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Overview

  • Supplier
    GeneTex
  • Product Name
    Nucleolin antibody [4E2]
  • Delivery Days Customer
    9
  • Applications
    ImmunoFluorescence, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    400
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID4691
  • Target name
    NCL
  • Target description
    nucleolin
  • Target synonyms
    C23; Nsr1; nucleolin
  • Host
    Mouse
  • Isotype
    IgG1
  • Scientific Description
    Nucleolin (NCL), a eukaryotic nucleolar phosphoprotein, is involved in the synthesis and maturation of ribosomes. It is located mainly in dense fibrillar regions of the nucleolus. Human NCL gene consists of 14 exons with 13 introns and spans approximately 11kb. The intron 11 of the NCL gene encodes a small nucleolar RNA, termed U20. [provided by RefSeq, Jul 2008]
  • Reactivity
    Bovine, Human
  • Storage Instruction
    2°C to 8°C,-20°C or -80°C
  • UNSPSC
    12352203

References

  • Efficient recovery of the RNA-bound proteome and protein-bound transcriptome using phase separation (OOPS). Villanueva E et al., 2020 Aug, Nat Protoc
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  • Full-length NF-kappaB repressing factor contains an XRN2 binding domain. Alexandrova J et al., 2020 Feb 28, Biochem J
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  • Synergistic inhibition of lung cancer cell invasion, tumor growth and angiogenesis using aptamer-siRNA chimeras. Lai WY et al., 2014 Mar, Biomaterials
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  • A cis-element with mixed G-quadruplex structure of NPGPx promoter is essential for nucleolin-mediated transactivation on non-targeting siRNA stress. Wei PC et al., 2013 Feb 1, Nucleic Acids Res
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