NUDT1 Antibody

Cusabio

NUDT1 Antibody

20

ImmunoFluorescence, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

NUDT1

nudix hydrolase 1

MTH1, oxidized purine nucleoside triphosphate hydrolase, 2-hydroxy-dATP diphosphatase, 7,8-dihydro-8-oxoguanine triphosphatase, 8-oxo-7,8-dihydrodeoxyguanosine triphosphatase, 8-oxo-7,8-dihydroguanosine triphosphatase, 8-oxo-dGTPase, methylated purine nucleoside triphosphate hydrolase, mutT human homolog 1, nucleoside diphosphate-linked moiety X motif 1, nucleoside diphosphate-linked moiety X-type motif 1, nudix (nucleoside diphosphate linked moiety X)-type motif 1, nudix motif 1

Rabbit

IgG

Oxidized purine nucleoside triphosphate hydrolase

Antimutagenic. Acts as a sanitizing enzyme for oxidized nucleotide pools, thus suppressing cell dysfunction and death induced by oxidative stress. Hydrolyzes 8-oxo-dGTP, 8-oxo-dATP and 2-OH-dATP, thus preventing misincorporation of oxidized purine nucleoside triphosphates into DNA and subsequently preventing A:T to C:G and G:C to T:A transversions. Able to hydrolyze also the corresponding ribonucleotides, 2-OH-ATP, 8-oxo-GTP and 8-oxo-ATP. Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA.

Human

-20°C or -80°C

41116161