NVP ADW 742

AbMole BioScience

NVP ADW 742

9

475488-23-4

Chemical

Research Use Only

C28H31N5O

453.58

Nvp-adw742 (ADW742) is an orally active, selective igF-1R tyrosine kinase inhibitor with an IC50 of 0.17 uM. Nvp-adw742 inhibited insulin receptor (InsR) with IC50 of 2.8 uM. Nvp-adw742 induces multipotent anti-proliferation/pro-apoptosis in tumor cells.

NC1=NC=NC2=C1C(=C[N]2C3CC(C3)CN4CCCC4)C5=CC(=CC=C5)OCC6=CC=CC=C6

12352200