NVP-AEW541 [475489-16-8]

MedChem Express

NVP-AEW541 [475489-16-8]

5

475489-16-8

Research Use Only

99.92

C27H29N5O

439.55

NVP-AEW541 (AEW541 ) is an orally active inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) with an IC50 value of 0.15 microM. NVP-AEW541 also inhibits InsR, IC50 with a value of 0.14 microM. NVP-AEW541 has antitumor activity[1].

NC1=C2C(N([C@@H]3C[C@@H](C3)CN4CCC4)C=C2C5=CC=CC(OCC6=CC=CC=C6)=C5)=NC=N1

-20°C,2°C to 8°C

12352200