Bio-Connect

NVP-BHG712 isomer

ORB1089635
Biorbyt
CAS Number2245892-85-5
Product group Chemicals
Molecular Weight503.489
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Overview

  • Supplier
    Biorbyt
  • Product Name
    NVP-BHG712 isomer [2245892-85-5]
  • Delivery Days Customer
    10
  • CAS Number
    2245892-85-5
  • Certification
    Research Use Only
  • Molecular Formula
    C26H20F3N7O
  • Molecular Weight
    503.489
  • Scientific Description
    NVP-BHG712 isomer is a regioisomer of NVP-BHG712, which shows conserved non-bonded binding to EPHA2 and EPHB4. BHG-712, is a EphB4 kinase inhibitor and BCR-ABL inhibitor. NVP-BHG712 inhibits EphB4 kinase activity in the low nanomolar range in cellular assays showed high selectivity for targeting the EphB4 kinase when profiled against other kinases in biochemical as well as in cell based assays.
  • SMILES
    C(NC1=CC=CC(C(F)(F)F)=C1)(=O)C1=CC=C(C)C(NC2=NC(C3=CC=CN=C3)=NC3=NN(C)C=C32)=C1
  • UNSPSC
    12352200