NVP-BHG712 isomer
ORB1089635
CAS Number2245892-85-5
Product group Chemicals
Molecular Weight503.489
Overview
- SupplierBiorbyt
- Product NameNVP-BHG712 isomer [2245892-85-5]
- Delivery Days Customer10
- CAS Number2245892-85-5
- CertificationResearch Use Only
- Molecular FormulaC26H20F3N7O
- Molecular Weight503.489
- Scientific DescriptionNVP-BHG712 isomer is a regioisomer of NVP-BHG712, which shows conserved non-bonded binding to EPHA2 and EPHB4. BHG-712, is a EphB4 kinase inhibitor and BCR-ABL inhibitor. NVP-BHG712 inhibits EphB4 kinase activity in the low nanomolar range in cellular assays showed high selectivity for targeting the EphB4 kinase when profiled against other kinases in biochemical as well as in cell based assays.
- SMILESC(NC1=CC=CC(C(F)(F)F)=C1)(=O)C1=CC=C(C)C(NC2=NC(C3=CC=CN=C3)=NC3=NN(C)C=C32)=C1
- UNSPSC12352200
![NVP-BHG712 isomer [2245892-85-5]](https://www.targetmol.com/group3/M00/36/0D/CgoaEGayNXiEUTvFAAAAAGU2-zw795.png)