NVP-DPP728 [247016-69-9]

MedChem Express

NVP-DPP728 [247016-69-9]

10

247016-69-9

Research Use Only

C15H18N6O

298.34

NVP-DPP728 is a potent, reversible and nitrile-dependent dipeptidyl peptidase IV (DPP-IV) inhibitor. NVP-DPP728 can inhibit human DPP-IV amidolytic activity with a Ki of 11 nM. NVP-DPP728 inhibits degradation of glucagon-like peptide-1 (GLP-1) and thereby potentiates insulin release in response to glucose intake. NVP-DPP728 can be used for researching diabetes[1].

N#CC(C=N1)=CC=C1NCCNCC(N2[C@@H](CCC2)C#N)=O

12131703